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The US Food and Drug Administration (FDA) remains the key issue for investors in the pharmaceuticals and healthcare sector, on Tuesday by global investment banking firm Jefferies. The investment firm's officials met investors in Asia to discuss healthcare sector - pharma and services. "The FDA remains the key issue for investors. FDA issues dominated most conversations. We highlighted to investors how the issues are cultural and cannot have a short term fix. These will require substantial re-training, changes in incentive policies and strict monitoring through consultants and internal compliance," the note said.